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Keep track of Carefully (one)pentobarbital will minimize the extent or effect of fentanyl transdermal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Intently. Coadministration of fentanyl with CYP3A4 inducers may lead to a lower in fentanyl plasma concentrations, lack of efficacy or, possibly, improvement of a withdr

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